We focus our research in four areas:

  • Electrodialysis for Salt Purification

    Electrodialysis for Salt Purification

    In electrodialysis, an electrical potential drives ions across membranes to effect separations. However, typical ion-exchange membranes show minimal selectivity between monovalent and divalent ions, which is important for applications such as water softening and salt purification. In contrast, we recently found that polyelectrolyte multilayers adsorbed on cation-exchange membranes give rise to an electrodialysis K+/Mg2+ selectivity >90.

  • Modified Membranes for Protein Purification

    Modified Membranes for Protein Purification

    We modify membranes with polyelectrolyte multilayers and then derivatize them with affinity groups that capture specific proteins.

  • Oil-Water Separations

    Oil-Water Separations

    This work is investigating the fouling resistance of new hydrophilic membrane coatings as well as the mechanism by which these coatings reject oil and resist fouling.

  • Rapid Antibody Digestion in Protease-Containing Membranes

    Rapid Antibody Digestion in Protease-Containing Membranes

    Proteolytic digestion followed by mass spectrometry (MS) analysis of the resulting peptides is the most common method to characterize antibodies and investigate post-translational modifications. This work develops digestion in protease-containing membranes for rapid (<1 min), controlled digestion.